Endocrine Abstracts

Background: Type 2 Diabetes (T2DM), though a rare condition in children, is increasing in the paediatric population. The British Paediatric Surveillance Unit (BPSU) reporting framework is used to understand the clinical course and epidemiology of rare diseases in children.Aim: To estimate the UK incidence of Type 2 diabetes (T2DM) in children aged <17 years and to compare with data collected a decade before. To characterize clinical features at diagn...

Introduction: Assessing cortisol status is a key endocrine investigation, to identify those who need glucocorticoid replacement or emergency sickness cover either due to primary or secondary cortisol deficiency or after long-term/high dose steroid treatment causing Hypothalamic-Pituitary-Adrenal axis (HPAA) suppression. A short synacthen test (SST) measuring cortisol levels after administration of Synthetic ACTH at time zero, 30 and 60 minutes is commonly used. A normal respon...